I love Housing Works
It's an advocacy and services organization for people living with HIV and AIDS *and* it's a great used bookstore and cafe with free wifi.
And they sell knishes, which I've yet to try; but the mere fact of their existence pleases me. Plus, I've just noticed a very odd mannequin holding a key and a cane, standing crosslegged against a wall, atop a bookshelf. Bonus points for that.